LC120 protocol · PepGuide

Standard

50–100u

0.5–1 mL · 1–3×/week

IM upper outer glute preferred; SubQ acceptable. 1 mL/week is most common maintenance.

Off

2–4 weeks

Reassess at 16–20 weeks. No mandatory off if tolerated.

Phase	How often	Dose	Units	Notes
Standard	1–3×/week	0.5–1 mL	50–100u	IM upper outer glute preferred; SubQ acceptable. 1 mL/week is most common maintenance.
Off	2–4 weeks	–	–	Reassess at 16–20 weeks. No mandatory off if tolerated.

Cycle & timing

Cycle: Ongoing 8–12 week blocks. Reassess at 16–20 weeks.

Timing: 3×/week IM, anytime; typically AM.

Where: IM upper outer glute preferred; SubQ acceptable.

What to expect

Energy and fat-loss adjunct effect builds over 4–8 weeks alongside diet/exercise.

Men & women

Unisex lipolytic / carnitine blend, dose by protocol; no meaningful sex difference. Avoid in pregnancy.

Recommended mixes

Vial	Water	Strength
10 ml	Solution, no reconstitution needed	Methionine 15 mg/mL; Choline Cl 50 mg/mL; L-Carnitine 50 mg/mL; Dexpanthenol 5 mg/mL

10 ml: 1 unit = 0.15 mg

Storage

MixedSolution: refrigerate 36–46°F. Use within 30 days. Protect from light.

Don't use if: Component allergies (B12, riboflavin, lecithin, choline, methionine, lidocaine) · Hypothyroid medication, separate by 4 hours · Severe hepatic impairment (choline metabolism) · Pregnancy and lactation, specific compounding required · Bleeding disorders or anticoagulants (relative), bruising risk

Side effects

Garlic/sulfur taste post-injection (methionine), mild flushing, injection-site sting.

Drug interactions

Warfarin: L-carnitine and choline blends can potentiate, monitor INR if combining; Levothyroxine: separate by 4 hours, choline/B-vitamins affect absorption; Anticoagulants / antiplatelets (DOACs, aspirin, clopidogrel): bruising risk with phosphatidylcholine; Insulin / antidiabetics: B-complex may shift glucose, recheck log if dosing changes; Methotrexate, trimethoprim, phenytoin: deplete folate / B12; coordinate with prescriber; Lidocaine blends (LC526): avoid other caines same session, additive cardiac effects; Stimulants / phentermine: additive CV load with high-dose lipotropics, monitor BP/HR

Labs

Compound-specific: CBC + CMP baseline; no compound-specific markers routinely required; Baseline B12, folate, MMA, homocysteine (methylation markers); TSH at baseline (B12 deficiency masks hypothyroidism); Liver enzymes (choline metabolism); Hematocrit (B12 raises RBC, polycythemia risk in some)

What these labs mean →

Warnings

Compounded products, composition varies; request the pharmacy’s COA; B12 (cyanocobalamin) contains cobalt, allergy possible; Methionine elevates homocysteine in some individuals; L-Carnitine: TMAO conversion concern in CV disease (controversial, baseline lipids); Injection-site reactions common with phosphatidylcholine

Patient education

Fishy odor from choline/L-carnitine is normal, not allergic; Inject slowly to reduce stinging; Don’t use with warfarin without physician guidance (potentiation risk); Request exact ingredient list and concentrations from your compounder

These apply on top of the universal safety rules.

Pairs well with

GLP-1s

fat-loss adjunct

L-Carnitine standalone

additive

L-Carnitine

SS-31 / NAD+

mitochondrial

SS-31 (Elamipretide) NAD+

Avoid with

Sulfa allergy

theoretical methionine

Can LC120 + L-Carnitine share a syringe?

Can share a syringe. Both are water-based. Combine them if you dose on the same schedule and site.

What it does

Lipo-C, classic lipotropic blend: Methionine + Choline + L-Carnitine + Dexpanthenol (B5). No B12. Empower-style formula. Methionine + Choline: hepatic VLDL export. L-Carnitine: mitochondrial fat oxidation.

References

peptidedosages PubMed thepeptidereport

From the guide, page 54.