Lipo-C protocol · PepGuide

Standard

100u

1 mL · M/W/F

Phosphatidylcholine lipotropic injection.

High

200u

2 mL · M/W/F

Upper range, only if you tolerated lower doses well.

Phase	How often	Dose	Units	Notes
Standard	M/W/F	1 mL	100u	Phosphatidylcholine lipotropic injection.
High	M/W/F	2 mL	200u	Upper range, only if you tolerated lower doses well.

Cycle & timing

Cycle: Ongoing or 8–12 weeks during weight loss protocols.

Timing: Daily or 3×/week, anytime; typically AM for energy bump.

Where: Abdomen or upper outer thigh.

What to expect

Liver function and fat metabolism improvement over 4–8 weeks. Works best alongside caloric restriction and GLP-1 therapy.

Men & women

Unisex lipotropic injection, dose by protocol, no cycle effect. Avoid in pregnancy.

Recommended mixes

Vial	Water	Strength
10 mg	Solution, no reconstitution needed	Phosphatidylcholine-based formulation

10 mg: U-100 syringe

Storage

MixedSolution: refrigerate. Use within 28 days.

Don't use if: Component allergies (B12, riboflavin, lecithin, choline, methionine, lidocaine) · Hypothyroid medication, separate by 4 hours · Severe hepatic impairment (choline metabolism) · Pregnancy and lactation, specific compounding required · Bleeding disorders or anticoagulants (relative), bruising risk

Side effects

Injection-site stinging (phosphatidylcholine). Fishy odour.

Drug interactions

Warfarin: L-carnitine and choline blends can potentiate, monitor INR if combining; Levothyroxine: separate by 4 hours, choline/B-vitamins affect absorption; Anticoagulants / antiplatelets (DOACs, aspirin, clopidogrel): bruising risk with phosphatidylcholine; Insulin / antidiabetics: B-complex may shift glucose, recheck log if dosing changes; Methotrexate, trimethoprim, phenytoin: deplete folate / B12; coordinate with prescriber; Lidocaine blends (LC526): avoid other caines same session, additive cardiac effects; Stimulants / phentermine: additive CV load with high-dose lipotropics, monitor BP/HR

Labs

Compound-specific: CBC + CMP baseline; no compound-specific markers routinely required; Baseline B12, folate, MMA, homocysteine (methylation markers); TSH at baseline (B12 deficiency masks hypothyroidism); Liver enzymes (choline metabolism); Hematocrit (B12 raises RBC, polycythemia risk in some)

What these labs mean →

Warnings

Compounded products, composition varies; request the pharmacy’s COA; B12 (cyanocobalamin) contains cobalt, allergy possible; Methionine elevates homocysteine in some individuals; L-Carnitine: TMAO conversion concern in CV disease (controversial, baseline lipids); Injection-site reactions common with phosphatidylcholine

Patient education

Fishy odor from choline/L-carnitine is normal, not allergic; Inject slowly to reduce stinging; Don’t use with warfarin without physician guidance (potentiation risk); Request exact ingredient list and concentrations from your compounder

These apply on top of the universal safety rules.

Pairs well with

GLP-1 agonists

amplified fat loss

CJC-1295 No DAC + Ipamorelin

full body recomp

CJC-1295 (No DAC) + Ipamorelin

Vitamin B12

energy + mood

Vitamin B12

Tesamorelin

visceral fat

Tesamorelin

Avoid with

No significant contraindications

Can Lipo-C + CJC-1295 (No DAC) + Ipamorelin share a syringe?

Can share a syringe. Both are water-based. Combine them if you dose on the same schedule and site.

What it does

Lipotropic phosphatidylcholine injection, hepatic fat mobilisation, liver health, and metabolic support. Phosphatidylcholine is the primary hepatic fat transport molecule.

Approved drug

Approved weight-loss drugs are far better proven: semaglutide (Wegovy), tirzepatide (Zepbound), orforglipron (Foundayo, oral, 2026), plus phentermine, Qsymia, Contrave and orlistat.

References

researchdosing peptidedosages PubMed thepeptidereport

From the guide, page 58.