MIC Blend protocol

Standard

100u

1 mL · M/W/F

Methionine 25 + Inositol 50 + Choline 50 + B12 1 mg/mL.

Daily

50u

0.5 mL · Daily

Lower daily alternative.

Phase	How often	Dose	Units	Notes
Standard	M/W/F	1 mL	100u	Methionine 25 + Inositol 50 + Choline 50 + B12 1 mg/mL.
Daily	Daily	0.5 mL	50u	Lower daily alternative.

Cycle & timing

Cycle: Ongoing with weight loss protocols.

Timing: Daily or 3×/week, anytime; typically AM.

Where: SubQ or IM upper outer thigh.

What to expect

Energy from B12 rapid. Fat metabolism improvement over 4–8 weeks. Standard lipotropic adjunct with GLP-1 therapy.

Men & women

Unisex lipotropic (methionine / inositol / choline), dose by protocol. Avoid in pregnancy.

Recommended mixes

Vial	Water	Strength
10 mg	Solution, no reconstitution needed	Methionine 25 mg/mL; Inositol 50 mg/mL; Choline 50 mg/mL; B12 1 mg/mL

10 mg: 1 unit = 0.25 mg

Storage

MixedSolution: refrigerate. Use within 30 days.

Don't use if: Component allergies (B12, riboflavin, lecithin, choline, methionine, lidocaine) · Hypothyroid medication, separate by 4 hours · Severe hepatic impairment (choline metabolism) · Pregnancy and lactation, specific compounding required · Bleeding disorders or anticoagulants (relative), bruising risk

Side effects

Mild injection-site reactions. Fishy odour (choline).

Drug interactions

Warfarin: L-carnitine and choline blends can potentiate, monitor INR if combining. Levothyroxine: separate by 4 hours, choline/B-vitamins affect absorption. Anticoagulants / antiplatelets (DOACs, aspirin, clopidogrel): bruising risk with phosphatidylcholine. Insulin / antidiabetics: B-complex may shift glucose, recheck log if dosing changes. Methotrexate, trimethoprim, phenytoin: deplete folate / B12; coordinate with prescriber. Lidocaine blends (LC526): avoid other caines same session, additive cardiac effects. Stimulants / phentermine: additive CV load with high-dose lipotropics, monitor BP/HR.

Labs

Compound-specific: Liver enzymes AST/ALT (baseline), baseline hepatic function before starting. Baseline B12, folate, MMA, homocysteine (methylation markers). TSH at baseline (B12 deficiency masks hypothyroidism). Liver enzymes (choline metabolism). Hematocrit (B12 raises RBC, polycythemia risk in some).

What these labs mean →

Warnings

Compounded products, composition varies; request the pharmacy's COA. B12 (cyanocobalamin) contains cobalt, allergy possible. Methionine elevates homocysteine in some individuals. L-Carnitine: TMAO conversion concern in CV disease (controversial, baseline lipids). Injection-site reactions common with phosphatidylcholine.

Patient education

Fishy odor from choline/L-carnitine is normal, not allergic. Inject slowly to reduce stinging. Don't use with warfarin without physician guidance (potentiation risk). Request exact ingredient list and concentrations from your compounder.

These apply on top of the universal safety rules.

Pairs well with

GLP-1 agonists

lipotropic stack

LC120 / LC216 / LC526

Lipo-C variants

LC120 LC216 LC526

HHB

B-vitamins

HHB

Avoid with

B-vitamin allergy

Severe hepatic disease

choline metabolism

Can MIC Blend + LC120 share a syringe?

Can share a syringe. Both are water-based. Combine them if you dose on the same schedule and site.

What it does

Classic MIC + B12 lipotropic, Methionine + Inositol + Choline + B12 for hepatic fat metabolism and energy. Methionine: fat transport and detox. Inositol: lipid metabolism and insulin signalling. Choline: hepatic VLDL export.

Approved drug

Approved weight-loss drugs are far better proven: semaglutide (Wegovy), tirzepatide (Zepbound), orforglipron (Foundayo, oral, 2026), plus phentermine, Qsymia, Contrave and orlistat.

References

peptidedosages PubMed thepeptidereport

From the guide, page 67.